Browsing by Contributors Chan, ATC

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2010A small molecule inhibitor of NF-κB, dehydroxymethylepoxyquinomicin (DHMEQ), suppresses growth and invasion of nasopharyngeal carcinoma (NPC) cellsLui, VWY; Tsao, SW; Wong, JHT; Umezawa, K; Ho, Y; Wong, EYL; Ng, MHL; Cheng, SH; Tsang, CM; Chan, ATC
2013Activity of the MEK inhibitor selumetinib (AZD6244; ARRY-142886) in nasopharyngeal cancer cell linesChan, ATC; Ng, PKS; Cheng, SH; Ng, MH; Tsui, SKW; Ho, K; Lau, CPY; Cheung, CS; Lui, VWY; Ma, BBY; Hui, EP; Tsao, SW
2010An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-beta-d-ribo-pentofuranosyl)cytosine (ECyd), elicits antitumor effect via TP53-induced Glycolysis and Apoptosis Regulator (TIGAR) downregulationLui, VWY; Tsao, SW; Lau, CPY; Cheung, CSF; Ho, K; Ng, MHL; Cheng, SH; Hong, B; Tsang, CM; Lei, KIK; Yamasaki, Y; Mita, A; Chan, ATC
2003Comparative proteomic study of an immortalized normal nasopharyngeal epithelial cell and an Esptein-Barr virus positive nasopharyngeal cell line using isotope-coded affinity tags and mass spectrometryPang, RTK; Poon, TCW; Chan, CML; Tsao, GSW; Huang, DP; Chan, ATC
2009Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cellsLui, VWY; Yau, DM; Wong, EY; Ng, YK; Lau, CPK; Ho, Y; Chan, JPL; Hong, B; Ho, K; Cheung, CS; Tsao, SW; Chan, ATC; Tsang, CM
2011FGF8b oncogene mediates proliferation and invasion of Epstein-Barr virus-associated nasopharyngeal carcinoma cells: Implication for viral-mediated FGF8b upregulationLui, VWY; Tsao, SW; Yau, DMS; Cheung, CSF; Wong, SCC; Chan, AKC; Zhou, Q; Wong, EYL; Lau, CPY; Lam, EKY; Hui, EP; Hong, B; Hui, CWC; Chan, ASK; Ng, PKS; Ng, YK; Lo, KW; Tsang, CM; Tsui, SKW; Chan, ATC
2006Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylationYing, J; Li, H; Seng, TJ; Langford, C; Srivastava, G; Tsao, SW; Putti, T; Murray, P; Chan, ATC; Tao, Q
2011Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activationLui, VWY; Tsao, SW; Hong, B; Hui, EP; Ng, MHL; Cheng, SH; Sung, FL; Tsang, CM; Chan, ATC
2011Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell deathLui, VWY; Tsao, SW; Wong, EYL; Ho, K; Ng, PKS; Lau, CPY; Tsui, SKW; Tsang, CM; Cheng, SH; Ng, MHL; Ng, YK; Lam, EKY; Hong, B; Lo, KW; Mok, TSK; Chan, ATC; Mills, GB
2012K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr Virus (EBV)-associated nasopharyngeal carcinoma cellsTsao, SW; Lui, VWY; Ng, YK; Wong, EYL; Lau, CPY; Chan, JPL; Wong, SCC; Chan, ASK; Kwan, MPC; Tsang, CM; Lai, PBS; Chan, ATC
2008OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivationCui, Y; Ying, Y; Van Hasselt, A; Ng, KM; Yu, J; Zhang, Q; Jin, J; Liu, D; Rhim, JS; Rha, SY; Loyo, M; Chan, ATC; Srivastava, G; Tsao, GSW; Sellar, GC; Sung, JJY; Sidransky, D; Tao, Q
2008Proteomic comparison of nasopharyngeal cancer cell lines C666-1 and NP69 identifies down-regulation of annexin II and β 2-tubulin for nasopharyngeal carcinomaChan, CML; Wong, SCC; Lam, MYY; Hui, EP; Chan, JKC; Lo, ESF; Cheuk, W; Wong, MCK; Tsao, SW; Chan, ATC
2009STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitroLui, VWY; Tsao, SW; Wong, EYL; Ho, Y; Hong, B; Wong, SCC; Tao, Q; Choi, GCG; Au, TCC; Ho, K; Yau, DMS; Ma, BBY; Hui, EP; Chan, ASK; Tsang, CM; Grandis, JR; Chan, ATC
2010The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell linesTsao, SW; Ma, BBY; Lui, VWY; Hui, EP; Lau, CPY; Ho, K; Ng, MHL; Cheng, SH; Chan, ATC
2012The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomasLi, L; Ying, J; Li, H; Zhang, Y; Shu, X; Fan, Y; Tan, J; Cao, Y; Chan, ATC; Tao, Q; Srivastava, G; Tsao, SW
2007The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomasSrivastava, G; Tsao, GSW; Chan, SL; Cui, Y; Van Hasselt, A; Li, H; Jin, H; Ng, KM; Wang, Y; Lee, KY; Zhong, S; Robertson, KD; Rha, SY; Chan, ATC; Tao, Q