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|Title:||Identification of microRNAs that target Id-1 in esophageal cancer|
|Authors:||Han, L;Li, B;Tsao, SW;Cheung, A|
|Publisher:||American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/|
|Description:||Poster Presentations - Non-Coding RNAs as Cancer Biomarkers: abstract no. 1959|
Inhibitor of DNA binding-1 (Id-1) belongs to a family of helix-loop-helix (HLH) proteins that lack the fundamental domain for DNA binding. Since Id-1 is overexpressed in esophageal squamous cell carcinoma (ESCC), and its expression level is associated with cancer invasion and metastasis, suppression of Id-1 may have therapeutic significance. MicroRNAs (miRNAs), which constitute non-coding small RNAs of around 22-nucleotides and negatively regulate gene expression as post-transcriptional regulator, were reported to be involved in carcinogenesis. However, there is limited information about the miRNAs ...
|Standard no:||The 104th Annual Meeting of the American Association for Cancer Research (AACR 2013), Washington, DC, PA., 6-10 April 2013. In Cancer Research, 2013, v. 73 n. 8, suppl. 1, abstract no. 1959|
8, suppl. 1
|Appears in Collections:||Department of Anatomy|
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