Please use this identifier to cite or link to this item: http://dl.umsu.ac.ir/handle/10722/54239
Title: Nano hemostat solution: immediate hemostasis at the nanoscale
Authors: EllisBehnke, RG;Liang, YX;Tay, DKC;Wu, W;So, KF;Kau, PWF;Schneider, GE;Zhang, S
subject: Hemostasis;Nanotechnology;Self-assembling peptide;Surgery;Trauma
Year: 2006
Publisher: Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/nanomed
United States
Description: Hemostasis is a major problem in surgical procedures and after major trauma. There are few effective methods to stop bleeding without causing secondary damage. We used a self-assembling peptide that establishes a nanofiber barrier to achieve complete hemostasis immediately when applied directly to a wound in the brain, spinal cord, femoral artery, liver, or skin of mammals. This novel therapy stops bleeding without the use of pressure, cauterization, vasoconstriction, coagulation, or cross-linked adhesives. The self-assembling solution is nontoxic and nonimmunogenic, and the breakdown products are amino acids, which are tissue building blocks that can be used to repair the site of injury. Here we report the first use of nanotechnology to achieve complete hemostasis in less than 15 seconds, which could fundamentally change how much blood is needed during surgery of the future. © 2006.
URI: http://www.scopus.com/mlt/select.url?eid=2-s2.0-33845287137&selection=ref&src=s&origin=recordpage
http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1549-9634&volume=2&issue=4&spage=207&epage=215&date=2006&atitle=Nano+hemostat+solution:+immediate+hemostasis+at+the+nanoscale+
http://hub.hku.hk/handle/10722/54239
Standard no: Nanomedicine: Nanotechnology, Biology, And Medicine, 2006, v. 2 n. 4, p. 207-215
10.1016/j.nano.2006.08.001
215
124249
1549-9634
4
17292144
eid_2-s2.0-33845287137
207
2
Appears in Collections:Department of Anatomy

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