Please use this identifier to cite or link to this item: http://dl.umsu.ac.ir/handle/10722/67414
Title: Telomerase activation in human cancers
Authors: Tsao, SW;Zhang, DK;Cheng, RYS;Wan, TSK
Year: 1998
Publisher: Zhonghua Yixuehui. The Journal's web site is located at http://www.cmj.org/
China
Description: Objective To review the background of telomerase activation and the methodology involved in its determination, and the clinico-pathological significance of telomerase activation in human cancers. Data sources An English-language literature search using MEDLINE (1966-1997) and bibliographic reviews of textbooks and review articles. Results Progressive shortening of telomeres was associated with continuous cell division in normal somatic cells. Telomerase was activated in most cancer cells and immortal germ cells to maintain their telomeric lengths. The occurrence and clinical pathological significance of telomerase activation was evaluated in various types of human cancer. Conclusions Telomerase activation is a common event in human cancers and may be as a useful marker for malignant cells. Telomerase may also be a therapeutic target for cancer treatment.
URI: http://www.scopus.com/mlt/select.url?eid=2-s2.0-0032129561&selection=ref&src=s&origin=recordpage
http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0366-6999&volume=111&issue=8&spage=745&epage=750&date=1998&atitle=Telomerase+activation+in+human+cancers
http://hub.hku.hk/handle/10722/67414
Standard no: Chinese Medical Journal, 1998, v. 111 n. 8, p. 745-750
750
33616
WOS:000075504700018
0366-6999
8
11245033
eid_2-s2.0-0032129561
745
111
Appears in Collections:Department of Anatomy

Files in This Item:
Click on the URI links for accessing contents.


Items in HannanDL are protected by copyright, with all rights reserved, unless otherwise indicated.