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Title: The Effects of Progesterone, Serum Gonadotrophin & Testosterone Propionate on Histology & Total Ascorbic Acid Content of the Adrenal of the Rat
Authors: Kar, A B;Roy, A C;Karkun, J N
subject: Intramuscular Injections;Pituitary Adrenocorticotrophin;Ascorbic acid;Depletion
Year: 1953
Description: Intramuscular injections of progesterone, serum gonadotrophtn and testosterone propionate cause.atrophic changes and decline in ascorbic acid content of the rat's adrenal cortex.The severity of cellular atrophy and the extent of depletion of ascorbic acid, however, are more marked in the androgen recipients. than in the rest of the experimental animals. A definite interrelationship exists between the histololaical response and the ascorbic acid content in the hormone-treated animals whIch suggest a lowered secretory activity of the adrenal cortex. These responses are probably mediated through a diminished output of pituitary adrenocorticotrophine .
Standard no: Journal of Scientific and Industrial Research1953,12B,470-73
Appears in Collections:Endocrinology

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