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|Title:||Agents Acting on the Central Nervous System: Part VIlIs- 5-subsituted 6, 7,8,9- tetrahydro - SH - benzocyc1oheptenes.|
|Authors:||Khanna, J M;Chak, I M;Anand, Nitya|
|subject:||Central Nervous System;anti-inflammatory action;pharmacological evaluation;hydrazines|
|Description:||The synthesis and pharmacological evaluation of certain 5-substituted amino-6,7,S,9-tetrahydro- 5H- benzocycloheptenes, 1-(6,7 ,S,9-tetrahydro-5H -benzocycloheptenyl) hydrazines, 5- (r -diethylamino) propyl-6, 7,S,9- tetrahydro-5H -benzocycloheptene and 5-(2-piperidylmethyl) - 6,7 ,S,9-tetrahydro- 5H-benzocycloheptene have been carried out. 5-Amino-6,7,S,9-tetrahydro-5H- benzocycloheptene shows a strong antipyretic effect and a weak anti-inflammatory action, while 5-hydroxy- 5-(2-pyridylmethyl)- 6,7,S,9- tetrahydro- 5H - benzocycloheptene shows anti -amphetamine action.|
|Standard no:||Indian Journal of Chemistry,1967,5,347|
|Appears in Collections:||Medicinal and Process Chemistry|
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