Please use this identifier to cite or link to this item: http://dl.umsu.ac.ir/handle/Hannan/23092
Title: Drugs Acting on CNS: Syntheses of 2-Substituted& 2,3-Disubstituted Benzo( 6,7) quinazoline-4 -ones.
Authors: GUPTA, C M;BHADURI, A P;KHANNA, K M
subject: CNS depressants;sodium hydroxide;2-Substituted;2,3-disubstituted
Year: 1968
Description: A series of 2-substituted and 2,3-disubstituted benzo(6,7)quinazoline-4-ones have been synthesized as possible CNS depressants. 2-Substituted products, viz. hydrazino, phenylhydrazino and amino, have been obtained by the reaction of 2-ethylthio-benzo(6,7) quinazolin-4-one with hydrazine, phenylhydrazine, and primary and secondary amines. The 2,3-disubstituted derivatives have been obtained by the reaction of 2-mercapto-3-phenyl-benzo(6,7)quinazoline- 4-one with appropriate alkyl, arylalkyl, dialkylamino-alkyl halides in the presence of alcoholic sodium hydroxide. Some of the compounds exhibit CNS-depressant activity at high dosage.
URI: http://hdl.handle.net/123456789/553
Standard no: Indian journal of chemistry,6,1968,621,623.
Appears in Collections:Medicinal and Process Chemistry

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