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Title: Histaminergic Angioedema
Authors: Busse, Paula J.;Smith, Tukisa
Year: 2017
Publisher: Elsevier Inc
Abstract: Angioedema is frequently categorized into histamine- or bradykinin-mediated disease. It is critical to determine the underlying mediator of symptoms as it directs treatment. Histaminergic angioedema is the most frequent cause of angioedema. It is classified as either acute (lasting <6 weeks) or chronic (symptoms >6 weeks). It is further classified into angioedema presenting with or without urticaria. Some patients with acute angioedema may have disease that becomes chronic. Mast cells and basophils are central to the underlying pathophysiology of histamine-mediated angioedema. The underlying treatments of histamine-mediated angioedema are antihistamines, corticosteroids, and epinephrine.
volume: Volume 37
issue: Issue 3
month: August
Appears in Collections:Immunology and Allergy Clinics of North America 2017

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