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PreviewIssue DateTitleContributor(s)
2018 JoMC Volume 61 Issue 1 January (3).pdf.jpg2018Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a β ‑ Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer ’ s DiseaseHa, Hee-jin; Kang, Dong Wook; Kim, Hyuk-min; Kang, Jin-mi; Ann, Jihyae; Hyun, Hyae Jung; Lee, Joon Hwan; Kim, Sae Hee; Kim, Hee; Choi, Kwanghyun; Hong, Hyun-seok; Kim, Youngho; Jo, Dong-gyu; Lee, Jiyoun; Lee, Jeewoo
2018 JoMC Volume 61 Issue 1 January (19).pdf.jpg2018A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the E ff ects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of AbuseSulima, Agnieszka; Jalah, Rashmi; Antoline, Joshua F G; Torres, Oscar B; Imler, Gregory H; Deschamps, R; Beck, Zoltan; Alving, Carl R; Jacobson, Arthur E; Rice, Kenner C; Matyas, Gary R
2018 JoMC Volume 61 Issue 10 May (17).pdf.jpg2018Positive Modulators of the N-Methyl-d-aspartate Receptor: Structure–Activity Relationship Study of Steroidal 3-HemiestersKrausova, Barbora; Slavikova, Barbora; Nekardova, Michaela; Hubalkova, Pavla; Vyklicky, Vojtech; Chodounska, Hana; Vyklicky, Ladislav; Kudova, Eva
2018 JoMC Volume 61 Issue 2 January (2).pdf.jpg2018A “ Click Chemistry Platform ” for the Rapid Synthesis of Bispeci fi c Molecules for Inducing Protein DegradationWurz, Ryan P; Dellamaggiore, Ken; Dou, Hannah; Javier, Noelle; Lo, Mei-chu; Mccarter, John D; Mohl, Dane; Sastri, Christine; Lipford, J Russell; Cee, Victor J
2018 JoMC Volume 61 Issue 10 May (10).pdf.jpg2018Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) InhibitorsMusil, Djordje; Buchstaller, Hans-peter; Eggenweiler, Hans-michael; Frech, Matthias; Ecker, Gerhard F
2018 JoMC Volume 61 Issue 2 January (1).pdf.jpg2018Regulating the Master Regulator : Controlling Ubiquitination by Thinking Outside the Active Site MiniperspectivePaiva, Stacey-lynn; Silva, Sara R; Araujo, Elvin D De; Gunning, Patrick T
2018 JoMC Volume 61 Issue 1 January (1).pdf.jpg2018Recent Advances in Structure-Based Drug Design Targeting Class A G Protein-Coupled Receptors Utilizing Crystal Structures and Computational SimulationsLee, Yoonji; Basith, Shaherin; Choi, Sun
2018 JoMC Volume 61 Issue 1 January (26).pdf.jpg2018University of Minnesota University of Michigan DRUG ANNOTATIONS EDITORS PERSPECTIVE EDITOR EDITOR EMERITUS EDITORIAL ADVISORY BOARDGeorg, Gunda; Wang, Shaomeng; Bolognesi, Maria Laura; Conway, Stuart; Cushman, Mark; Haskell-luevano, Carrie; Holzgrabe, Ulrike; Garcia-echeverria, Carlos; Zablocki, Jeff; Meanwell, Nicholas; Portoghese, Philip S; Aldrich, Courtney C; Blagg, Julian; Juillerat-jeannere
2018 JoMC Volume 61 Issue 10 May (26).pdf.jpg2018University of Minnesota University of Michigan DRUG ANNOTATIONS EDITORS PERSPECTIVE EDITOR EDITOR EMERITUS EDITORIAL ADVISORY BOARDGeorg, Gunda; Wang, Shaomeng; Bolognesi, Maria Laura; Conway, Stuart; Cushman, Mark; Denny, William; Haskell-luevano, Carrie; Garcia-echeverria, Carlos; Zablocki, Jeff; Meanwell, Nicholas; Portoghese, Philip S; Aldrich, Courtney C; Blagg, Julian; Juillerat-jeanneret,
2018 JoMC Volume 61 Issue 3 February (21).pdf.jpg2018Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766)Chessum, Nicola E A; Sharp, Swee Y; Caldwell, John J; Pasqua, A Elisa; Wilding, Birgit; Colombano, Giampiero; Collins, Ian; Ozer, Bugra; Richards, Meirion; Rowlands, Martin; Stubbs, Mark; Burke, Rosemary; Mcandrew, P Craig; Clarke, Paul A; Workman, Paul; Cheeseman, Matt
2018 JoMC Volume 61 Issue 10 May (8).pdf.jpg2018Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid ReceptorAmato, George S; Manke, Amruta; Harris, Danni L; Wiethe, Robert W; Vasukuttan, Vineetha; Snyder, Rodney W; Lefever, Timothy W; Cortes, Ricardo; Zhang, Yanan; Wang, Shaobin; Runyon, Scott P
2018 JoMC Volume 61 Issue 2 January (7).pdf.jpg2018Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Speci fi c ER α and ER β ActivityBoyle, Niamh M O; Barrett, Irene; Greene, Lisa M; Carr, Miriam; Fayne, Darren; Twamley, Brendan; Knox, Andrew J S; Keely, Niall O; Zisterer, Daniela M; Meegan, Mary J
2018 JoMC Volume 61 Issue 10 May (21).pdf.jpg2018Structure-Guided Design, Synthesis, and Characterization of Next-Generation Meprin β InhibitorsRamsbeck, Daniel; Hamann, Antje; Richter, Georg; Schlenzig, Dagmar; Geissler, Stefanie; Nykiel, Vera; Cynis, Holger; Schilling, Stephan; Buchholz, Mirko
2018 JoMC Volume 61 Issue 10 May (15).pdf.jpg2018Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor SubtypeYu, Rilei; Tae, Han-shen; Tabassum, Nargis; Shi, Juan; Jiang, Tao; Adams, David J
2018 JoMC Volume 61 Issue 3 February (1).pdf.jpg2018BACE ‑ 1 Inhibitors : From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer ’ s DiseasePrati, Federica; Bottegoni, Giovanni; Bolognesi, Maria Laura; Cavalli, Andrea
2018 JoMC Volume 61 Issue 10 May (1).pdf.jpg2018Relevance of Half-Life in Drug DesignSmith, Dennis A; Beaumont, Kevin; Maurer, Tristan S; Di, Li
2018 JoMC Volume 61 Issue 3 February (33).pdf.jpg2018David W. Piotrowski, * Kentaro Futatsugi, Agustin Casimiro-Garcia, Liuqing Wei, Matthew F. Sammons, Michael Herr, Wenhua Jiao, Sophie Y. Lavergne, Steven B. Co ff ey, Stephen W. Wright, Kun Song, Paula M. Loria, Mary Ellen Banker, Donna N. Petersen, and JPiotrowski, David W; Futatsugi, Kentaro; Casimiro-garcia, Agustin; Wei, Liuqing; Sammons, Matthew F; Herr, Michael; Jiao, Wenhua; Lavergne, Sophie Y; Co, Steven B; Wright, Stephen W; Song, Kun; Loria, Paula M; Banker, Mary Ellen; Petersen, Donna N; Bauman, Jonathan
2018 JoMC Volume 61 Issue 4 February (14).pdf.jpg2018Identi fi cation of [ 18 F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET ImagingBernard-gauthier, Vadim; Mossine, Andrew V; Mahringer, Anne; Aliaga, Arturo; Bailey, Justin J; Shao, Xia; Stau, Jenelle; Arteaga, Janna; Sherman, Phillip; Maison, Marilyn Grand; Kaplan, David R; Fricker, Gert; Rosa-neto, Pedro; Scott, Peter J H; Schirrmacher, Ralf
2018 JoMC Volume 61 Issue 3 February (42).pdf.jpg2018Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3)Kaniskan, H U; Eram, Mohammad S; Zhao, Kehao; Szewczyk, Magdalena M; Yang, Xiaobao; Schmidt, Keith; Luo, Xiao; Xiao, Sean; Dai, Miao; He, Feng; Zang, Irene; Lin, Ying; Li, Fengling; Dobrovetsky, Elena; Smil, David; Min, Sun-joon; Lin-jones, Jennifer; Schapira, Matthieu; At
2018 JoMC Volume 61 Issue 5 March (18).pdf.jpg2018Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side E ff ect Pro fi leRipa, Lena; Edman, Karl; Dearman, Matthew; Edenro, Goran; Hendrickx, Ramon; Ullah, Victoria; Chang, Hui-fang; Lepisto, Matti; Chapman, Dave; Geschwindner, Stefan; Wissler, Lisa; Svanberg, Petter; Lawitz, Karolina; Malmberg, Jesper; Nikitidis, Antonios; Olsson, Roine I; B