Please use this identifier to cite or link to this item:
Title: Pituitary Adenoma Volumetry with 3D Slicer
Authors: Egger, Jan;Kapur, Tina;Nimsky, Christopher;Kikinis, Ron
subject: Biology;Endocrine System;Endocrine Physiology;Pituitary;Computer Science;Algorithms;Computing Methods;Medicine;Oncology;Endocrine Tumors;Pituitaryadenomas;Radiology;Anatomy;Physiology;Cancers;Neoplasms
Year: 2012
Publisher: Public Library of Science
Description: In this study, we present pituitary adenoma volumetry using the free and open source medical image computing platform for biomedical research: (3D) Slicer. Volumetric changes in cerebral pathologies like pituitary adenomas are a critical factor in treatment decisions by physicians and in general the volume is acquired manually. Therefore, manual slice-by-slice segmentations in magnetic resonance imaging (MRI) data, which have been obtained at regular intervals, are performed. In contrast to this manual time consuming slice-by-slice segmentation process Slicer is an alternative which can be significantly faster and less user intensive. In this contribution, we compare pure manual segmentations of ten pituitary adenomas with semi-automatic segmentations under Slicer. Thus, physicians drew the boundaries completely manually on a slice-by-slice basis and performed a Slicer-enhanced segmentation using the competitive region-growing based module of Slicer named GrowCut. Results showed that the time and user effort required for GrowCut-based segmentations were on average about thirty percent less than the pure manual segmentations. Furthermore, we calculated the Dice Similarity Coefficient (DSC) between the manual and the Slicer-based segmentations to proof that the two are comparable yielding an average DSC of 81.97±3.39%.
Standard no: Egger, Jan, Tina Kapur, Christopher Nimsky, and Ron Kikinis. 2012. Pituitary adenoma volumetry with 3D slicer. PLoS ONE 7(12): e51788.
Appears in Collections:HMS Scholarly Articles

Files in This Item:
Click on the URI links for accessing contents.

Items in HannanDL are protected by copyright, with all rights reserved, unless otherwise indicated.