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|Abstract:||EDITORIALS 359 Standing on the Shoulders of Giants Joseph S. Alpert 361 Are We Cuddling up to Kissing Bugs? Patricia L. Dorn COMMENTARY 362 Over-testing: Why More Is Not Better Jerome Greenberg and Jonas B. Green REVIEWS 364 Diets to Prevent Coronary Heart Disease 1957-2013: What Have We Learned? James E. Dalen and Stephen Devries This thorough review outlines dietary recommendations and nutritional research since 1957. 370 Advances in the Diagnosis and Management of Asthma in Older Adults Mazen Al-Alawi, Tidi Hassan, and Sanjay H. Chotirmall Major challenges exist in performing and interpreting diagnostic tests and overcoming therapeutic issues unique to older adults with asthma. 379 Individual and Composite Study Endpoints: Separating the Wheat from the Chaff Robert Goldberg, Joel M. Gore, Bruce Barton, and Jerry Gurwitz This review provides the individual and combined endpoints and patient-reported outcomes typically used in clinical trials and prospective epidemiological investigations. PHYSICAL FINDINGS 385 Popeye Deformity—An Augenblick Diagnosis Shawn Chillag and Kim Chillag DIAGNOSTIC DILEMMAS 386 Coughing up Blood: Behçet’s Disease Jayanth Doss, James England, and Howard Fuchs 390 An Absolute Obstacle: Cardiac Metastasis of Synovial Sarcoma Kairav Vakil, Ahmad Raza, Marina Zakharova, Richard Madlon-Kay, Keith Skubitz, and Manish Patel IMAGES IN RADIOLOGY 393 Pinched: Superior Mesenteric Artery Syndrome Filippo Mearelli, Ferruccio Degrassi, Alessandro Agostino Occhipinti, Chiara Casarsa, Nicolò De Manzini, and Gianni Biolo A5 395 The Hypermetabolic Mushroom: Superior Vena Cava Syndrome Benjamin Coiffard, Xavier Elharrar, Thomas Vandemoortele, Sophie Laroumagne, Hervé Dutau, and Philippe Astoul CLINICAL RESEARCH STUDIES 398 Hepatitis C Screening Trends in a Large Integrated Health System Benjamin P. Linas, Haihong Hu, Devra M. Barter, and Michael Horberg “Baby Boomers” and people with no documented drug use history have low Hepatitis C (HCV) screening rates. Risk-targeted HCV screening resulted in low screening rates in groups with the highest prevalence of HCV. 406 Head CT Scan Overuse in Frequently Admitted Medical Patients Mina Owlia, Lan Yu, Christopher Deible, Marion A. Hughes, Franziska Jovin, and Gregory M. Bump Patients with frequent medical admissions are medically complex and undergo multiple CT scans in a year. The vast majority of head CT scans lack clinically significant findings; head CT scans should be ordered less frequently. 411 Patent Foramen Ovale and Migraine Attacks: A Systematic Review Philomena Z.Y. Lip and Gregory Y.H. Lip This systematic review demonstrates that migraine headache attack is associated with a higher prevalence of patent foramen ovale than in the general population. 421 Free-roaming Kissing Bugs, Vectors of Chagas Disease, Feed Often on Humans in the Southwest Stephen A. Klotz, Justin O. Schmidt, Patricia L. Dorn, Craig Ivanyi, Katherine R. Sullivan, and Lori Stevens Free-roaming kissing bugs frequently feed on humans. Some kissing bugs carry Trypanosoma cruzi, making them a previously unrecognized potential vector for transmission of Chagas disease in the US. 427 B-type Natriuretic Peptide and Clinical Judgment in the Detection of Exercise-induced Myocardial Ischemia Gino Lee, Seoung Mann Sou, Raphael Twerenbold, Tobias Reichlin, Shino Oshima, Thomas Hochgruber, Stephan Zürcher, Deborah Matter, Yunus Tanglay, Michael Freese, Ursina Honegger, Damian Wild, Katharina Rentsch, Stefan Osswald, Michael J. Zellweger, and Christian Mueller Combining clinical judgment with B-type natriuretic peptide levels increased the diagnostic accuracy regarding the presence of myocardial ischemia. 436 Low Fitness Partially Explains Resting Metabolic Rate Differences Between African American and White Women Robin P. Shook, Gregory A. Hand, Xuewen Wang, Amanda E. Paluch, Robert Moran, James R. Hébert, Damon L. Swift, Carl J. Lavie, and Steven N. Blair African American women have a lower resting metabolic rate, compared to their white peers; low cardiorespiratory fitness explained one quarter of this difference. 443 Survival After Community Diagnosis of Early-stage Non-small Cell Lung Cancer Norma F. Kanarek, Craig M. Hooker, Luckson Mathieu, Hua-Ling Tsai, Charles M. Rudin, James G. Herman, and Malcolm V. Brock In addition to the state of disease, tumor size, and age at diagnosis, each week the referral interval is lengthened conveys a 5% increase in the risk of death. AJM ONLINE Please note that articles with an “e” page designation are available only in the online version of the Journal at www.amjmed.com. A6 CLINICAL COMMUNICATIONS TO THE EDITOR e1 Adrenal Suppression with Cushingoid Features from Inhaled Corticosteroid Therapy in an Adult Asthmatic Patient Michael A. Tsoukas, Preetha Krishnamoorthy, Brent J. Richards, Carmela Pepe, and Stavroula Christopoulos e3 Case Report and Review of the Literature: Floating Aortic Thrombus Vincenzo A. Barbato, Robert Castro, and Aaron Goertz e5 A Granulomatous Chronic Disease Alexander J. Stockdale, Claire L. Mackintosh, Katherine E. Roberston, and Kristjan O. Helgason e7 Sister Mary Joseph’s Node Abraham M. Ittyachen, Smitha Krishnamoorthy, and Abdulla Shanavas e9 Left Main Coronary Artery Stent Thrombosis: A Challenging Case Kyle Pfahl and Konstantinos Dean Boudoulas e11 First in Man: Adipose-derived Stromal Vascular Fraction Cells May Promote Restorative Cardiac Function Zain Khalpey, Rajesh Janardhanan, John Konhilas, and Courtney Hemphill LETTERS e13 Open Access Publication, Journal Policy, and Scientific Community Viroj Wiwanitkit and Shunhai Qu e15 The Reply Vinay Prasad and Neal Shea e17 Electrocardiography in Pericarditis and ST-Elevation Myocardial Infarction: Timing of Observation Is Critical Lovely Chhabra and David H. Spodick e19 The Reply Juan Cinca, Xavier Rossello, Alfredo Bardají, and Fernando Worner e21 An Evaluation of a Clinical Decision Support Tool Christopher Nguyen and Ware Kuschner e23 The Reply Ali S. Raja, Luciano M. Prevedello, Ivan K. Ip, Aaron Sodickson, and Ramin Khorasani e25 Lowering Blood Glucose Without Increasing Mortality David L. Keller e27 Associated Factors of Acute Myocardial Infarction in Patients with Systemic Sclerosis Tomoyuki Kawada e29 ‘Check the Box’ Medicine Not Practiced by Choice Ronald L. Hirsch e31 Check the Box Medicine Daniel Gonzalo Grassi BRIEF OBSERVATION 450 Insulin-derived Amyloidosis and Poor Glycemic Control: A Case Series Terumasa Nagase, Keiichi Iwaya, Yoshiki Iwaki, Fumio Kotake, Ryuji Uchida, Tsunao Oh-i, Hidenori Sekine, Kazuhiro Miwa, Satoshi Murakami, Tomotada Odaka, Masahiko Kure, Yoko Nemoto, Masayuki Noritake, and Yoshiya Katsura AAIM PERSPECTIVES 455 Direct Observation of Residents: A Model for an Assessment System Anthony A. Donato CLASSIFIED ADS B1 Positions available A7|
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