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Title: Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes
Authors: Xu, Tao;Brandmaier, Stefan;Messias, Ana C;Herder, Christian;Draisma, Harmen H M;Demirkan, Ayse;Yu, Zhonghao;Ried, Janina S;Haller, Toomas;Heier, Margit;Campillos, Monica;Fobo, Gisela;Stark, Renee;Holzapfel, Christina;Adam, Jonathan;Chi, Shen;Rotter, Markus;Panni, Tommaso;Quante, Anne S;He, Ying;Prehn, Cornelia;Roemisch-Margl, Werner;Kastenmüller, Gabi;Willemsen, Gonneke;Pool, René;Kasa, Katarina;van Dijk, Ko Willems;Hankemeier, Thomas;Meisinger, Christa;Thorand, Barbara;Ruepp, Andreas;Hrabé de Angelis, Martin;Li, Yixue;Wichmann, H-Erich;Stratmann, Bernd;Strauch, Konstantin;Metspalu, Andres;Gieger, Christian;Suhre, Karsten;Adamski, Jerzy;Illig, Thomas;Rathmann, Wolfgang;Roden, Michael;Peters, Annette;van Duijn, Cornelia M;Boomsma, Dorret I;Meitinger, Thomas;Wang-Sattler, Rui
Year: Oct-2015
Abstract: Metformin is used as a first-line oral treatment for type 2 diabetes (T2D). However, the underlying mechanism is not fully understood. Here, we aimed to comprehensively investigate the pleiotropic effects of metformin.
ISSN: 10.2337/dc15-0658
Appears in Collections:Diabetes Care 2015

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