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2016 JMC Volume 59 Issue 10 May (17).pdf.jpg2016Identi fi cation and Development of 2,3- Dihydropyrrolo[1,2 ‑ a ]quinazolin-5(1 H ) ‑ one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting ComplexSutherell, Charlotte L.
2016 JMC Volume 59 Issue 8 April (28).pdf.jpg2016Discovery of N ‑ (3-((1-Isonicotinoylpiperidin-4-yl)oxy)-4- methylphenyl)-3-(tri fl uoromethyl)benzamide (CHMFL-KIT-110) as a Selective, Potent, and Orally Available Type II c ‑ KIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs)Wang, Qiang
2016 JMC Volume 59 Issue 4 February (11).pdf.jpg2016Identi fi cation of SNAIL1 Peptide-Based Irreversible Lysine-Speci fi c Demethylase 1 ‑ Selective InactivatorsInactivators, Demethylase Selective; Solomon, Viswas Raja; Zhan, Peng; Suzuki, Miki; Ogasawara, Daisuke; Shigenaga, Akira
2016 JMC Volume 59 Issue 7 April (26).pdf.jpg2016Structure-Based Design of an Iminoheterocyclic β ‑ Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central A β in Nonhuman PrimatesMandal, Mihirbaran; Wu, Yusheng; Li, Guoqing; Buevich, Alexei; Caldwell, John P; Liu, Xiaoxiang; Mazzola, Robert D; Orth, Peter; Strickland, Corey; Voigt, Johannes; Wang, Hongwu; Zhu, Zhaoning; Chen, Xia; Grzelak, Michael; Hyde, Lynn A; Kuvelkar, Reshma; Leach, Prescott
2016 JMC Volume 59 Issue 3 February (32).pdf.jpg2016Structure − Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4 ‑ Methylester-Rakicidin ASang, Feng; Ding, Yahui; Wang, Jinghan; Sun, Bingxia; Sun, Jianlei; Geng, Yan; Zhang, Zhang; Ding, Ke; Wu, Ling-ling; Liu, Jian-wei; Bai, Cuigai; Yang, Guang; Zhang, Quan; Li, Lu-yuan; Chen, Yue
2016 JMC Volume 59 Issue 6 March (22).pdf.jpg2016Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute PancreatitisShore, Emma R; Awais, Muhammad; Kershaw, Neil M; Gibson, Robert R; Pandalaneni, Sravan; Latawiec, Diane; Wen, Li; Javed, Muhammad A; Criddle, David N; Berry, Neil; Neill, Paul M O; Lian, Lu-yun; Sutton, Robert
2016 JMC Volume 59 Issue 7 April (23).pdf.jpg2016Structure Property Relationships of Carboxylic Acid IsosteresLassalas, Pierrik; Gay, Bryant; Lasfargeas, Caroline; James, Michael J; Tran, Van; Vijayendran, Krishna G; Brunden, Kurt R; Kozlowski, Marisa C; Thomas, Craig J; Smith, Amos B; Huryn, Donna M; Ballatore, Carlo
2016 JMC Volume 59 Issue 1 January (15).pdf.jpg2016Reinvestigating Old Pharmacophores: Are 4 ‑ Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?Terzic, Natasa; Konstantinovic, Jelena; Burojevic, Jovana; Srbljanovic, Jelena; Verbic, Tatjana; Sciotti, Richard J; Pecic, Stevan; Taramelli, Donatella
2016 JMC Volume 59 Issue 2 January (17).pdf.jpg2016Structure − Activity Relationship of Azaindole-Based Glucokinase ActivatorsCeuninck, De; Bernard, Catherine; Ktorza, Alain; Perron-sierra, Francoise
2016 JMC Volume 59 Issue 7 April (41).pdf.jpg2016Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation ofIannazzo, Laura; Soroka, Daria; Fonvielle, Matthieu; Compain, Fabrice
2016 JMC Volume 59 Issue 1 January (3).pdf.jpg2016Structural Insights into the Competitive Binding of Diclofenac and Naproxen by Equine Serum AlbuminSekula, Bartosz; Bujacz, Anna
2016 JMC Volume 59 Issue 7 April (3).pdf.jpg2016Small Molecule CXCR3 AntagonistsAndrews, Stephen P; Cox, Rhona J
2016 JMC Volume 59 Issue 5 March (10).pdf.jpg2016De fi nitive Metabolite Identi fi cation Coupled with Automated Ligand Identi fi cation System (ALIS) Technology: A Novel Approach to Uncover Structure − Activity Relationships and Guide Drug Design in a Factor IXa Inhibitor ProgramZhang, Ting; Liu, Yong; Yang, Xianshu; Martin, Gary E; Yao, Huifang; Shang, Jackie; Bugianesi, Randal M; Ellsworth, Kenneth P; Sonatore, Lisa M; Nizner, Peter; Sherer, Edward C; Hill, Susan E; Knemeyer, Ian W; Geissler, Wayne M; Dandliker, Peter J; Helmy, Roy; Wood, Haro
2016 JMC Volume 59 Issue 1 January (35).pdf.jpg2016Correction to Discovery of 2 ‑ Pyridinone Aminals : A Prodrug Strategy to Advance a Second Generation of HIV ‑ 1 Integrase Strand Transfer InhibitorsRaheem, Izzat T; Walji, Abbas M; Klein, Daniel; Sanders, John M; Powell, David A; Abeywickrema, Pravien; Barbe, Guillaume; Bennet, Amrith; Childers, Karla; Christensen, Melodie; Clas, Sophie Dorothee; Dubost, David; Embrey, Mark; Grobler, Jay; Hafey, Michael J; Hartingh
2016 JMC Volume 59 Issue 5 March (4).pdf.jpg2016Development of a Novel Nonpeptidic 18 F ‑ Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission TomographyWenzel, Barbara; Mollitor, Jan; Deuther-conrad, Winnie; Dukic-stefanovic, Sladjana; Kranz, Mathias; Vraka, Chrysoula; Teodoro, Rodrigo; Gu, Robert; Donat, Cornelius K; Ludwig, Friedrich-alexander; Smits, Rene; Wadsak, Wolfgang; Mitterhauser, Markus; Steinbach, Jo; Hoep
2016 JMC Volume 59 Issue 2 January (12).pdf.jpg2016Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial ActivityGoodreid, Jordan D; Janetzko, John; Maria, John P Santa; Wong, Keith S; Leung, Elisa; Eger, Bryan T; Bryson, Steve; Pai, Emil F; Gray-owen, Scott D; Walker, Suzanne; Houry, Walid A; Batey, Robert A
2016 JMC Volume 59 Issue 5 March (11).pdf.jpg2016Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase III βRutaganira, Florentine U; Fowler, Melissa L; Mcphail, Jacob A; Gelman, Michael A; Nguyen, Khanh; Xiong, Anming; Dornan, Gillian L; Tavshanjian, Brandon; Glenn, S; Shokat, Kevan M; Burke, John E
2016 JMC Volume 59 Issue 2 January (15).pdf.jpg2016Design, Synthesis, and Pharmacological Evaluation of Novel N ‑ Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual InhibitorsRodrigues, Daniel A; Ferreira-silva, Guilherme A; Ferreira, Ana C S; Fernandes, Renan A; Kwee, Jolie K; Anna, Carlos M R Sant; Ionta, Marisa; Fraga, Carlos A M
2016 JMC Volume 59 Issue 4 February (23).pdf.jpg2016Design and Synthesis of Simpli fi ed Largazole Analogues as Isoform- Selective Human Lysine Deacetylase InhibitorsReddy, Damodara N; Ballante, Flavio; Chuang, Timothy; Pirolli, Adele; Marrocco, Biagina; Marshall, Garland R; Universita, Sapienza; Moro, P A
2016 JMC Volume 59 Issue 7 April (40).pdf.jpg2016Detection of in Vitro Metabolite Formation of Le fl unomide: A Fluorescence Dynamics and Electronic Structure StudySharma, Poornima; Gangopadhyay, Debraj; Mishra, Phool Chand; Mishra, Hirdyesh; Singh, Ranjan K