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PreviewIssue DateTitleContributor(s)
2016 JMC Volume 59 Issue 10 May (17).pdf.jpg2016Identi fi cation and Development of 2,3- Dihydropyrrolo[1,2 ‑ a ]quinazolin-5(1 H ) ‑ one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting ComplexSutherell, Charlotte L.
2016 JMC Volume 59 Issue 8 April (28).pdf.jpg2016Discovery of N ‑ (3-((1-Isonicotinoylpiperidin-4-yl)oxy)-4- methylphenyl)-3-(tri fl uoromethyl)benzamide (CHMFL-KIT-110) as a Selective, Potent, and Orally Available Type II c ‑ KIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs)Wang, Qiang
2016 JMC Volume 59 Issue 6 March (10).pdf.jpg2016Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identi fi ed by Fragment ScreeningBorthwick, Jennifer A; Ancellin, Nicolas; Bertrand, Sophie M; Bingham, Ryan P; Carter, Paul S; Chung, Chun-wa; Churcher, Ian; Dodic, Nerina; Francis, Peter L; Hobbs, Andrew; Jamieson, Craig; Pickett, Stephen D; Smith, Sarah E; Somers, Donald O N; Spitzfaden, Claus; Suck
2016 JMC Volume 59 Issue 5 March (25).pdf.jpg2016MutantsCheng, Hengmiao; Nair, Sajiv K; Murray, Brion W; Almaden, Chau; Bailey, Simon; Baxi, Sangita; Behenna, Doug; Cho-schultz, Sujin; Dalvie, Deepak; Dinh, Dac M; Edwards, Martin P; Feng, Jun Li; Ferre, Rose Ann; Gajiwala, Ketan S; Hemkens, Michelle D; Jackson-fisher, Amy; Ja
2016 JMC Volume 59 Issue 6 March (25).pdf.jpg2016Hydroxypyrimidine-2,4-diones as Selective Active Site Inhibitors of HIV Reverse Transcriptase-Associated RNase H: Design, Synthesis, and Biochemical EvaluationsTang, Jing; Liu, Feng; Nagy, Eva; Miller, Lena; Kirby, Karen A; Wilson, Daniel J; Wu, Bulan; Sara, Stefan G; Parniak, Michael A; Wang, Zhengqiang
2016 JMC Volume 59 Issue 4 February (10).pdf.jpg2016Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4(1)Hu, Martin; Lucas, Xavier; Weitzel, Gerhard; Ostrovskyi, Dmytro; Breit, Bernhard; Gerhardt, Stefan; Einsle, Oliver; Gu, Stefan; Wohlwend, Daniel
2016 JMC Volume 59 Issue 3 February (10).pdf.jpg2016Indole Based Weapons to Fight Antibiotic Resistance: A Structure − Activity Relationship StudyLepri, Susan; Buonerba, Federica; Goracci, Laura; Velilla, Irene; Ruzziconi, Renzo; Schindler, Bryan D; Seo, Susan M; Kaatz, Glenn W; Cruciani, Gabriele
2016 JMC Volume 59 Issue 7 April (42).pdf.jpg2016Novel Combretastatin-2-aminoimidazole Analogues as Potent Tubulin Assembly Inhibitors: Exploration of Unique Pharmacophoric Impact of Bridging Skeleton and Aryl MoietyChaudhary, Vikas; Venghateri, Jubina B; Dhaked, Hemendra P S; Bhoyar, Anil S; Guchhait, Sankar K; Panda, Dulal
2016 JMC Volume 59 Issue 4 February (19).pdf.jpg2016Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure − Activity Relationship StudySchiedel, Matthias; Rumpf, Tobias; Karaman, Berin; Lehotzky, Attila; Ola, Judit; Gerhardt, Stefan; Sippl, Wolfgang; Einsle, Oliver; Jung, Manfred
2016 JMC Volume 59 Issue 5 March (5).pdf.jpg2016Inhibiting the In fl ammasome: A Chemical PerspectiveBaldwin, Alex G; Brough, David; Freeman, Sally
2016 JMC Volume 59 Issue 6 March (40).pdf.jpg2016MutT Homolog 1 (MTH1): The Silencing of a TargetPapeo, Gianluca
2016 JMC Volume 59 Issue 7 April (8).pdf.jpg2016Mu-Fa Zou, † , ○ Thomas M. Keck, † , ∇ , ○ Vivek Kumar, † Prashant Donthamsetti, § , ¶ Mayako Michino, ‡ Caitlin Burzynski, † Catherine Schweppe, † Alessandro Bonifazi, † R. Benjamin Free, ⊥ David R. Sibley, ⊥ Aaron Janowsky, # , ∥ Lei Shi, ‡ , ◆ JonathanZou, Mu-fa; Keck, Thomas M; Kumar, Vivek; Donthamsetti, Prashant; Michino, Mayako; Burzynski, Caitlin; Schweppe, Catherine; Bonifazi, Alessandro; Free, R Benjamin; Sibley, David R; Janowsky, Aaron; Shi, Lei; Javitch, Jonathan A; Newman, Amy Hauck
2016 JMC Volume 59 Issue 6 March (36).pdf.jpg2016Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo ActivitySchenkel, Laurie B; Olivieri, Philip R; Boezio, Alessandro A; Deak, Holly L; Emkey, Renee; Grace, Russell F; Gunaydin, Hakan; Guzman-perez, Angel; Lee, Josie H; Te, Yohannes; Wang, Weiya; Youngblood, Beth D; Yu, Violeta L; Zhang, Maosheng; Gavva, Narender R; Lehto, Sony
2016 JMC Volume 59 Issue 1 January (5).pdf.jpg2016Novel Tacrine − Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer ’ s Disease: Design, Synthesis, Biological Evaluation, and X ‑ ray CrystallographyZha, Xiaoming; Lamba, Doriano; Zhang, Lili; Lou, Yinghan; Xu, Changxu; Kang, Di; Chen, Li; Xu, Yungen; Zhang, Luyong; Simone, Angela De; Samez, Sarah; Pesaresi, Alessandro; Stojan, Jure; Lopez, Manuela G; Egea, Javier; Andrisano, Vincenza; Bartolini, Manuela
2016 JMC Volume 59 Issue 6 March (38).pdf.jpg2016Potent and Selective Agonists of Sphingosine 1 ‑ Phosphate 1 (S1P 1 ): Discovery and SAR of a Novel Isoxazole Based SeriesWatterson, Scott H; Guo, Junqing; Spergel, Steve H; Langevine, Charles M; Moquin, Robert V; Shen, Ding Ren; Yarde, Melissa; Cvijic, Mary Ellen; Banas, Dana; Liu, Richard; Suchard, Suzanne J; Gillooly, Kathleen; Taylor, Tracy; Rex-rabe, Sandra; Shuster, David J; Mcintyre
2016 JMC Volume 59 Issue 3 February (12).pdf.jpg2016New 4 ‑ Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group IIIHuynh, Tri H V; Erichsen, Mette N; Tora, S; Goudet, Cyril; Sagot, Emmanuelle; Assaf, Zeinab; Thomsen, Christian; Brodbeck, Robb; Stensbøl, Tine B; Bjørn-yoshimoto, Walden E; Nielsen, Birgitte; Pin, Jean-philippe; Ge, Thierry; Bunch, Lennart
2016 JMC Volume 59 Issue 6 March (35).pdf.jpg2016Sanjib Bhakta, † Nicolo ̀ Scalacci, ‡ , ⊥ Arundhati Maitra, † Alistair K. Brown, # , ‡ Saiprasad Dasugari, ‡ Dimitrios Evangelopoulos, § , ∇ Timothy D. McHugh, § Parisa N. Mortazavi, † Alexander Twist, ‡ Elena Petricci, ∥ Fabrizio Manetti, * , ∥ and DanieBhakta, Sanjib; Scalacci, Nicolo; Maitra, Arundhati; Brown, Alistair K; Dasugari, Saiprasad; Petricci, Elena; Manetti, Fabrizio; Castagnolo, Daniele
2016 JMC Volume 59 Issue 4 February (8).pdf.jpg2016New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain InhibitionCiulli, Alessio
2016 JMC Volume 59 Issue 6 March (2).pdf.jpg2016Rho Kinase ( ROCK ) Inhibitors and Their Therapeutic PotentialFeng, Yangbo; Lograsso, Philip V; Defert, Olivier; Li, Rongshi
2016 JMC Volume 59 Issue 2 January (2).pdf.jpg2016Pan Assay Interference Compounds ( PAINS ) and Other Promiscuous Compounds in Antifungal ResearchPouliot, Martin; Jeanmart, Stephane