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PreviewIssue DateTitleContributor(s)
2016 JMC Volume 59 Issue 10 May (17).pdf.jpg2016Identi fi cation and Development of 2,3- Dihydropyrrolo[1,2 ‑ a ]quinazolin-5(1 H ) ‑ one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting ComplexSutherell, Charlotte L.
2016 JMC Volume 59 Issue 8 April (28).pdf.jpg2016Discovery of N ‑ (3-((1-Isonicotinoylpiperidin-4-yl)oxy)-4- methylphenyl)-3-(tri fl uoromethyl)benzamide (CHMFL-KIT-110) as a Selective, Potent, and Orally Available Type II c ‑ KIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs)Wang, Qiang
2016 JMC Volume 59 Issue 4 February (11).pdf.jpg2016Identi fi cation of SNAIL1 Peptide-Based Irreversible Lysine-Speci fi c Demethylase 1 ‑ Selective InactivatorsInactivators, Demethylase Selective; Solomon, Viswas Raja; Zhan, Peng; Suzuki, Miki; Ogasawara, Daisuke; Shigenaga, Akira
2016 JMC Volume 59 Issue 5 March (44).pdf.jpg2016Shuang-Yan Wang, † , ‡ Younes Larsen, † Cristina Vara Navarrete, † Anders A. Jensen, * , † Birgitte Nielsen, † Ali Al-Musaed, † Karla Frydenvang, † Jette Sandholm Kastrup, * , † Darryl S. Pickering, * , † and Rasmus Prætorius Clausen * , † †Wang, Shuang-yan; Larsen, Younes; Navarrete, Cristina Vara; Jensen, Anders A; Nielsen, Birgitte; Al-musaed, Ali; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S; Clausen, Rasmus Prætorius
2016 JMC Volume 59 Issue 2 January (21).pdf.jpg2016Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors ( hCAIs ): Synthesis by Pd Nanocatalyst-Mediated Suzuki − Miyaura Reaction , Enzyme Inhibition , and X ‑ ray Crystallographic StudiesCornelio, Benedetta; Laronze-cochard, Marie; Ceruso, Mariangela; Ferraroni, Marta; Rance, Graham A; Carta, Fabrizio; Khlobystov, Andrei N; Fontana, Antonella; Supuran, Claudiu T; Sapi, Janos
2016 JMC Volume 59 Issue 7 April (27).pdf.jpg2016Purine ( N ) ‑ Methanocarba Nucleoside Derivatives Lacking an Exocyclic Amine as Selective A 3 Adenosine Receptor AgonistsTosh, Dilip K; Ciancetta, Antonella; Warnick, Eugene; Connor, Robert O; Chen, Zhoumou; Gizewski, Elizabeth; Crane, Steven; Gao, Zhan-guo; Auchampach, John A; Salvemini, Daniela; Jacobson, Kenneth A
2016 JMC Volume 59 Issue 1 January (25).pdf.jpg2016Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M 1 Muscarinic Acetylcholine ReceptorMistry, Shailesh N; Jo, Manuela; Lim, Herman; Vinh, Natalie B; Sexton, Patrick M; Capuano, Ben; Christopoulos, Arthur; Lane, J Robert; Scammells, Peter J
2016 JMC Volume 59 Issue 7 April (6).pdf.jpg2016Adrenoceptor Antagonist with Antiurinary Frequency E ff ects: Reducing Human Ether-a-go-go-Related Gene (hERG) LiabilitiesSakauchi, Nobuki; Kohara, Yasuhisa; Sato, Ayumu; Suzaki, Tomohiko; Imai, Yumi; Okabe, Yuichi
2016 JMC Volume 59 Issue 6 March (15).pdf.jpg2016Investigations of Enantiopure Nicotine Haptens Using an Adjuvanting Carrier in Anti-Nicotine Vaccine DevelopmentJacob, Nicholas T; Lockner, Jonathan W; Schlosburg, Joel E; Ellis, Beverly A; Eubanks, Lisa M; Janda, Kim D
2016 JMC Volume 59 Issue 5 March (30).pdf.jpg2016A Binding Site on IL-17A for Inhibitory Macrocycles Revealed by Hydrogen/Deuterium Exchange Mass SpectrometryEspada, Alfonso; Broughton, Howard; Jones, Spencer; Chalmers, Michael J; Dodge, A
2016 JMC Volume 59 Issue 3 February (13).pdf.jpg2016Novobiocin Analogues That Inhibit the MAPK PathwayHall, Jessica A; Seedarala, Sahithi; Zhao, Huiping; Garg, Gaurav; Ghosh, Suman; Blagg, Brian S J
2016 JMC Volume 59 Issue 7 April (4).pdf.jpg2016((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 InhibitorsAi, Teng; Wilson, Daniel J; More, Swati S; Xie, Jiashu; Chen, Liqiang
2016 JMC Volume 59 Issue 7 April (8).pdf.jpg2016Mu-Fa Zou, † , ○ Thomas M. Keck, † , ∇ , ○ Vivek Kumar, † Prashant Donthamsetti, § , ¶ Mayako Michino, ‡ Caitlin Burzynski, † Catherine Schweppe, † Alessandro Bonifazi, † R. Benjamin Free, ⊥ David R. Sibley, ⊥ Aaron Janowsky, # , ∥ Lei Shi, ‡ , ◆ JonathanZou, Mu-fa; Keck, Thomas M; Kumar, Vivek; Donthamsetti, Prashant; Michino, Mayako; Burzynski, Caitlin; Schweppe, Catherine; Bonifazi, Alessandro; Free, R Benjamin; Sibley, David R; Janowsky, Aaron; Shi, Lei; Javitch, Jonathan A; Newman, Amy Hauck
2016 JMC Volume 59 Issue 6 March (36).pdf.jpg2016Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo ActivitySchenkel, Laurie B; Olivieri, Philip R; Boezio, Alessandro A; Deak, Holly L; Emkey, Renee; Grace, Russell F; Gunaydin, Hakan; Guzman-perez, Angel; Lee, Josie H; Te, Yohannes; Wang, Weiya; Youngblood, Beth D; Yu, Violeta L; Zhang, Maosheng; Gavva, Narender R; Lehto, Sony
2016 JMC Volume 59 Issue 1 January (5).pdf.jpg2016Novel Tacrine − Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer ’ s Disease: Design, Synthesis, Biological Evaluation, and X ‑ ray CrystallographyZha, Xiaoming; Lamba, Doriano; Zhang, Lili; Lou, Yinghan; Xu, Changxu; Kang, Di; Chen, Li; Xu, Yungen; Zhang, Luyong; Simone, Angela De; Samez, Sarah; Pesaresi, Alessandro; Stojan, Jure; Lopez, Manuela G; Egea, Javier; Andrisano, Vincenza; Bartolini, Manuela
2016 JMC Volume 59 Issue 6 March (38).pdf.jpg2016Potent and Selective Agonists of Sphingosine 1 ‑ Phosphate 1 (S1P 1 ): Discovery and SAR of a Novel Isoxazole Based SeriesWatterson, Scott H; Guo, Junqing; Spergel, Steve H; Langevine, Charles M; Moquin, Robert V; Shen, Ding Ren; Yarde, Melissa; Cvijic, Mary Ellen; Banas, Dana; Liu, Richard; Suchard, Suzanne J; Gillooly, Kathleen; Taylor, Tracy; Rex-rabe, Sandra; Shuster, David J; Mcintyre
2016 JMC Volume 59 Issue 3 February (11).pdf.jpg2016Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein − Protein Interaction between Menin and Mixed Lineage Leukemia (MLL)Borkin, Dmitry; Pollock, Jonathan; Kempinska, Katarzyna; Purohit, Trupta; Li, Xiaoqin; Wen, Bo; Zhao, Ting; Miao, Hongzhi; Shukla, Shirish; He, Miao; Sun, Duxin; Cierpicki, Tomasz; Grembecka, Jolanta
2016 JMC Volume 59 Issue 6 March (35).pdf.jpg2016Sanjib Bhakta, † Nicolo ̀ Scalacci, ‡ , ⊥ Arundhati Maitra, † Alistair K. Brown, # , ‡ Saiprasad Dasugari, ‡ Dimitrios Evangelopoulos, § , ∇ Timothy D. McHugh, § Parisa N. Mortazavi, † Alexander Twist, ‡ Elena Petricci, ∥ Fabrizio Manetti, * , ∥ and DanieBhakta, Sanjib; Scalacci, Nicolo; Maitra, Arundhati; Brown, Alistair K; Dasugari, Saiprasad; Petricci, Elena; Manetti, Fabrizio; Castagnolo, Daniele
2016 JMC Volume 59 Issue 4 February (8).pdf.jpg2016New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain InhibitionCiulli, Alessio
2016 JMC Volume 59 Issue 6 March (2).pdf.jpg2016Rho Kinase ( ROCK ) Inhibitors and Their Therapeutic PotentialFeng, Yangbo; Lograsso, Philip V; Defert, Olivier; Li, Rongshi